Fetching details from the dictionary...
(not) in any way; in no way; at all
terribly; awfully; hopelessly
この問題はどうにも解決できなかった。
This problem couldn't be solved in any way.
どうにも気になって眠れない夜だった。
I couldn't help worrying and it was a sleepless night.
体調がどうにもすぐれないので休むことにした。
I decided to take a rest because I wasn't feeling well at all.