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shop; store; restaurant
someone who sells (something) or works as (something)
someone with a (certain) personality trait
house
roof
「家」 has other readings with different meanings.
あの花屋はいつも賑やかだ。
That flower shop is always lively.
あの家には誰が住んでいる。
Who lives in that house?
駅前にパン屋が新しくできた。
A new bakery opened in front of the station.