Fetching details from the dictionary...

between (e.g. two people); face to face
hindrance; impediment
prefix used for stress or emphasis
arrhythmic section of recitative
playing with only 2 players
counter for traditional dance songs
毎月の給料から税金の差し引きがされた。
Deductions were made from my salary.
二人は差しで酒を飲んだ。
The two of them drank together face to face.
不良品だったので差を出して返品しました。
I returned it after deducting the difference.