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fate; destiny (esp. as a mysterious force that binds two people together)
relationship (e.g. between two people); bond; link; connection
family ties; affinity
opportunity; chance (to meet someone and start a relationship)
pratyaya (indirect conditions, as opposed to direct causes)
narrow open-air veranda
「縁」 has other readings with different meanings.
コップの縁が欠けてしまったので捨てた。
I threw it away because the edge of the cup was chipped.
私は人との縁を大切にしている。
I value connections.
帽子の縁を下げて日差しを避けていた。
I lowered the brim of my hat to avoid the sunlight.