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wife; your wife; his wife; married lady; madam
奥おく様さまによろしくお伝えつたえください。
Please give my regards to your wife.
奥おく様さまはお元気げんきでいらっしゃいますか。
Is your wife doing well?
隣となりの奥おく様さまにお菓子かしをいただいた。
I received sweets from the lady next door.