to pin (someone) down; to hold down; to immobilize; to immobilise
to shut out (one's opponent); to keep (the opposing team) from scoring
to suppress; to control; to check; to curb
警官が犯人を押さえ込んだ。
The officer pinned down the suspect.
反発を押さえ込むのは難しい。
It is difficult to suppress opposition.
暴れる患者を看護師が押さえ込んでいた。
The nurse was holding down the struggling patient.