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crime
「罪」 has another reading with different meanings.
彼は罪を犯したことを深く後悔している。
He deeply regrets committing the crime.
無実の罪で捕まった人を助けたいと思う。
I want to help people caught for crimes they didn't commit.
彼女は罪の意識に苦しんでいるようだ。
She seems to be suffering from guilt.