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space (between); gap; interval; distance; stretch
period of time (during, while); duration; interval
between (two parties or things)
among (a group)
relations (between); relationship
midpoint; average; halfway; middle ground
「間」 has other readings with different meanings.
家と駅の間に公園がある。
There is a park between the house and the station.
その間、ずっと待っていた。
During that time, I kept waiting.
最近、二人の間に何か問題があるようだ。
There is a problem between the two of them.