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isolation; being alone; being friendless
その村は大雪で孤立してしまった。
The village became isolated due to heavy snow.
国際社会で孤立することは避けたい。
We want to avoid becoming isolated in the international community.
意見の相違から彼は職場で完全に孤立している状態だ。
He is in a state of isolation at his workplace.