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calamity; misfortune; disaster
旅行中に財布を盗まれるなんて災難だったね。
Having your wallet stolen while traveling was a disaster.
次々と災難が起こって本当に大変な年だった。
Disasters happened one after another, it was a really tough year.
災難続きでも諦めずに頑張ることが大切だ。
It's important not to give up even with continuous disasters.