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to lose
to miss (a chance, opportunity)
to lose (a loved one); to be bereaved of
to concede (goals, points, etc.)
彼は事故で両親を失ったんだよ。
He lost his parents in an accident.
一瞬の判断で大事なチャンスを失った。
Missed an important chance with one snap judgment.
仕事を失うのが怖くて頑張ってる。
I'm working hard because I'm afraid of losing my job.