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feeling in the hands (when striking, poking, etc.); (feeling of) resistance
response (to one's efforts); reaction; (having an) effect (on)
手応えのある試験だった。
It was a challenging exam.
面接で手応えを感じた。
I felt a positive response in the interview.
交渉に手応えがあったので期待している。
I felt a good response in negotiations so I'm hopeful.