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to handle; to manage; to deal with; to work with; to have experience with
to rear; to look after
彼はこれまでに数多くのプロジェクトを手懸けてきた。
He has worked on numerous projects to date.
若い頃から建築設計を手懸けている。
I have been involved in architectural design since I was young.
この出版社は児童書を多く手懸けていることで知られる。
This publisher is known for having worked on many children's books.