to firmly tighten (e.g. around neck, throat); to constrict; to squeeze; to bind; to wring; to screw in (e.g. a bulb)
to strongly press (someone); to crack down on; to pursue relentlessly; to keep under strict control; to put the screws on
to settle accounts
ロープをしっかり締め上げた。
He firmly tightened the rope.
会社は経費を締め上げてきた。
The company has been tightening expenses.
政府は輸入規制をさらに締め上げる方針だ。
The government plans to further tighten import regulations.