Fetching details from the dictionary...

to run into; to collide with; to crash into; to bump against
to come to the end of (a street)
to run into (difficulties, problems, etc.); to run up against
暗闇の中で壁に衝き当たって額を打った。
I bumped into a wall in the dark and hit my forehead.
この道をまっすぐ行くと大通りに衝き当たる。
If you go straight down this road, you'll reach the main street.
研究を進める中で大きな問題に衝き当たった。
I ran into a major problem as I advanced my research.