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serious disease; intractable disease; difficult-to-recover-from illness
彼女は難病と闘っている。
She is fighting an intractable disease.
新しい難病治療法が開発された。
A new treatment method for intractable diseases has been developed.
彼は難病の原因究明に人生を捧げた。
He dedicated his life to elucidating the causes of intractable diseases.