Fetching details from the dictionary...

to twist; to wrench; to turn (a tap, switch, etc.)
to twist (a body part); to bend; to sprain
to strangle (to death); to wring (an animal's neck)
to defeat easily; to beat
to make (a problem, design, etc.) intricate; to make peculiar; to make complicated
to manage to compose (a haiku, song, etc.)
ドアのノブをひねって部屋に入った。
I turned the door knob and entered the room.
ガスコンロのつまみを右にひねった。
I turned the gas stove knob to the right.
彼女はドアノブをひねっているが、鍵がかかっている。
She is turning the doorknob, but the door is locked.