Fetching details from the dictionary...

to lose; to be defeated
to succumb; to give in; to surrender; to yield
to be inferior to
to break out in a rash due to (e.g. lacquer, shaving, etc.)
to reduce the price; to give a discount; to throw in (something extra) for free
試合に負けてしまいました。
I ended up losing the match.
昨日のゲームで負けました。
I lost in yesterday's game.
絶対に負けたくないです。
I absolutely don't want to lose.