change; alteration
difference; distinction
something wrong; abnormality; unusual event; accident; incident
季節の変わり目は体調を崩しやすい。
It's easy to get sick at the change of seasons.
特に変わりなく元気にしています。
There's nothing in particular that has changed; I'm doing well.
時代の変わりとともに価値観も変わる。
Values change along with the changing times.