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irregularity; abnormality; anomaly
change of tone; transposition
modulation
機械の動作が急に変調した。
The machine's operation suddenly became erratic.
強い磁場で実験装置の信号が変調している。
In a strong magnetic field, the signal from the experimental apparatus is fluctuating abnormally.
長期の不眠から体調がついに変調した患者が増えている。
The number of patients whose health has finally gone out of order after long insomnia is rising.