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to get complicated; to grow worse; to turn sour
「拗れる」 has another reading with different meanings.
交渉が拗れて進展が難航しています。
Negotiations have gotten complicated and stalled.
風邪が拗れてついに肺炎になりました。
My cold got worse and turned into pneumonia.
問題が拗れる前に早めに解決しましょう。
Let's solve it before the problem gets worse.