to screw up (one's face); to scrunch up; to pucker up; to furrow (one's brow); to wrinkle
「顰める」 has another reading with different meanings.
誰もが顔を顰める。
Everyone screws up their face.
彼は不快そうに顔を顰めた。
He grimaced unpleasantly.
その話を聞いて眉を顰めてしまう。
Hearing that story makes me furrow my brow.