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to be contrary; to run counter (to); to conflict (with); to disagree (with)
二人の意見が鋭く相反した。
The two opinions conflicted sharply.
彼らの利益は常に相反している。
Their interests are always in conflict.
二つの方針が相反するときは上司に判断を仰ぐしかない。
When two policies conflict, there's no choice but to ask the boss for a ruling.