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to function well; to be capable; to have a keen sense (of taste, smell); to be shrewd
to work; to function well
to be possible (to do, use, etc.); to be able to
to taste (alcohol); to try
彼は鼻が利くので香水の違いが分かる。
He has a keen nose and can tell perfumes apart.
このエアコンはよく利くので夏も快適だ。
This air conditioner works well, so summer is comfortable.
この薬は頭痛によく利いた。
This medicine was very effective for the headache.