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with trouble; at great pains
rare; valuable; precious; long-awaited
kind; generous
specially; especially; expressly
せっかく作った料理が冷めてしまった。
The food I took trouble to make got cold.
せっかくの休みなので旅行に行こう。
Since it is a precious holiday, let us travel.
せっかくの休みなのに雨だ。
It's raining on my precious day off.