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to sever; to cut off
to suppress; to eradicate; to exterminate
to abstain (from); to give up
退路を断たれた兵士たちは最後まで戦った。
The soldiers, with their retreat cut off, fought to the end.
彼女は甘いものを断つと決心した。
She resolved to give up sweets.
悪い習慣を断って、健康的な生活を始めよう。
Let's cut out bad habits and start a healthy lifestyle.