to go to the top; to climb to the top; to ascend to the top; to reach the summit (e.g. of a mountain)
to be engrossed in; to be very enthusiastic about; to be infatuated with
彼は社長の座まで上り詰めた。
He climbed his way up to the company president's seat.
長い下積みの末に業界の頂点へ上り詰めている。
After a long apprenticeship he is climbing to the top of the industry.
誰もが上り詰めるわけではないが、努力は必ず糧になる。
Not everyone reaches the top, but effort is always a nourishment.