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altogether; entirely
「尽く」 has another reading with different meanings.
彼女の努力は尽く報われたと聞きました。
I heard that her efforts were entirely rewarded.
尽く成功したプロジェクトは珍しいですよ。
It's rare for a project to be entirely successful.
尽くの問題を解決してようやく完成しました。
After solving all the problems, it was finally completed.