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in spite of; despite; although
nonetheless; nevertheless; but; (and) yet
雨にもかかわらず試合は行われた。
The game was held despite the rain.
反対にもかかわらず計画を進めます。
We will proceed with the plan despite opposition.
努力にもかかわらず失敗に終わる。
Despite my efforts, it ends in failure.