to go through; to pierce; to penetrate
to stick to (opinion, principles, etc.); to carry out; to persist with; to keep (e.g. faith); to maintain (e.g. independence)
彼は信念を貫き通した人だ。
He is a person who stuck to his beliefs
最後まで姿勢を貫き通すべきだ。
You should maintain your stance to the end
矢が厚い板を貫き通した。
The arrow pierced through the thick board