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changing clothes; change of clothes
「着替え」 has another reading with different meanings.
週末に着替えを持って家族で温泉に行きます。
I'm going to the hot spring with a change of clothes.
旅行には三日分の着替えを持っていく。
I will bring three days' worth of clothes to change into for the trip.
汗をかいたので着替えを取りに戻った。
I sweated, so I went back to get a change of clothes.