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tiredness; fatigue
「疲れ」 has another reading with different meanings.
疲れが溜まったので休暇を取った。
I took a vacation because I was getting tired.
仕事の疲れをお風呂で癒している。
I heal my work tiredness in the bath.
今日の疲れはぐっすり眠れば取れる。
Today's tiredness will go away with a good sleep.